Lipodrene Hardcore Ephedra Reviews, Dangers & Legal Status
Lipodrene Hardcore markets itself as a new formulation of the original Lipodrene ephedra diet pills that are now banned.
This product is advertised as an “Extremely potent stimulant developed for hardcore athletes.”
Lipodrene Hardcore is manufactured by Hi Tech Pharmaceuticals and contains 25 mg of ephedra extract, without the ephedrine alkaloids. Other ingredients include Citrus Aurantium 60% Extract, Evodiamine, 5-Methoxytryptamine HCL and Yohimbe 8% Extract.
Does the new and improved version of this weight loss and energy-boosting supplement provide individuals with the results they are looking for? In this Lipodrene Hardcore review, we will discuss the effects, mechanisms side effects and results of this supplement. Click here to buy ephedra supplements online legally without a prescription.
Lipodrene Hardcore Review
Lipodrene Hardcore is produced by Hi-Tech Pharmaceuticals, a sports nutrition and dietary supplement manufacturer well-known to athletes and bodybuilders.
The product has been around since the early 1990s and can be found on store shelves as well as online venues. Hi-Tech Pharmaceuticals develops a large product line of bodybuilding supplements as well as diet pills and health products.
They originally introduced Lipodrene with Ephedra as a weight loss supplement to help men and women promote fat loss and suppress the appetite.
This product is designed to be a stronger formula compared to the original product line, with more stimulant-based ingredients. Lipodrene Hardcore markets itself as “The world’s most advanced weight-loss aid ever developed with rapid release technology – extreme thermogenic agent developed to eviscerate fat.”
Lipodrene Hardcore contains 25 mg ephedra extract along with a number of ingredients designed to boost energy. Note that the ephedra used in this product is from the Thermo-Z propriety blend and does not contain any of the banned ephedrine alkaloids.
When determining the effectiveness and possible results that can be expected from any dietary, weight loss, or energy-boosting product, ingredients are key.
Note that the ephedra extract used in this product does not contain any ephedrine alkaloids. This is akin to drinking decaffeinated coffee. To make up for the loss of ephedrine alkaloids, the makers of Lipodrene Hardcore have stacked their ephedra extract with a number of other ingredients that promote Central Nervous System stimulation.
Lipodrene Hardcore Ingredients
In addition to the 25 mg ephedra extract found in Lipodrene Hardcore, consumers will find Acacia rigidula extract. Hi-Tech pharmaceuticals distributed a press release about their supplements and stated that one compound found in Acacia rigidula was “more potent than both caffeine and ephedrine.” 
This herb is included in many diet pills because it contains BMPEA, which is considered to be a powerful stimulant. However, the FDA has ruled that Acacia rigidula extract does not meet their definition of a lawful ingredient for use in dietary supplements and is potentially dangerous.
BMPEA stands for (beta)-methylphenylamine. This stimulant is likened to speed due to its similarity in chemical structure to amphetamines. It can also cause a false positive on an amphetamine drug test.
The Acacia rigadula shrub, native to the southwestern United States, doesn’t naturally contain BMPEA. However, be aware that “special blends” created by dietary supplement manufacturers may include ingredients in their products that are not listed on the label – including ‘modified’ versions of Acacia rigidula or other ingredients that do contain BMPEA.
A number of stores carrying products with the component voluntarily removed supplements containing the ingredient , although disagreements regarding safety of the product continue.
Other ingredients found in Lipodrene Hardcore include:
- Citrus aurantium extract (60%) – aka Bitter Orange
- Yohimbe extract (bark) – 8%
- Yerba Mate extract
- Green tea extract (45 mg)
- Theobroma cocoa extract (25 mg)
- Cassia Nomame extract
- 6,7 dihydroxybergamottin
- 5-methoxytryptamine HCl
- Caffeine (200 mg)
Most of these ingredients work by stimulating the central nervous system, increase the body’s basal metabolic rate and promoting higher energy levels. This may indirectly lead to weight loss, so long as users stay active and follow a calorie-restricted diet.
Bitter orange is a natural plant extract that contains p-Synephrine, a primary protoalkaloid with some properties in common with ephedrine. It has been studied for its effects on weight loss, showing modest benefits.
In studies on individuals who are overweight or obese, bitter orange extract was combined with consumption of between 132 mg and 528 mg of caffeine daily. Bitter Orange (Citrus aurantium) was used up to 12 weeks in these studies and was found to promote short-term fat loss results.
Some results did show increased resting metabolic rate and increased calorie expenditure throughout the day. A few small studies have shown weight reduction of approximately 1.4 kg (equating to 2.9% of body fat) after six weeks of use.
In research trials, Bitter Orange extract and p-Synephrine are often combined with other herbal supplements including Yohimbe, caffeine, St. John’s Wort, Green tea, Guarana.
Such combinations make it difficult to measure the results of one component over another in order to determine which ingredients actually work for weight loss. 
Benefits and User Reviews
Lipodrene Hardcore is marketed to provide a number of benefits to users, such as:
- Significant boost in energy
- Stable energy levels with no extreme highs (feeling jittery) or energy crash when the product wears off.
- Appetite suppressant; stimulant ingredients block hunger signals to the brain so users feel less hungry and eat less at mealtime.
- Fat burning potential; ingredients found in Lipodrene Hardcore are perceived to trigger thermogenesis and greater metabolism.
Note that even though stimulants can enhance your metabolism, it is not always true that this will lead to weight loss. In order to burn body fat, you body needs to be in a state of negative energy balance. Many factors can influence this including diet, hormone balance, body type, height, weight, age, genetics and activity levels.
Use of a supplement like Lipodrene Hardcore might help you burn more calories, but in order to promote long-term weight loss results diet and lifestyle changes are necessary.
A number of Lipodrene Hardcore reviews can be found online. Reviews generally give this supplement high marks in regard to weight loss, with some claiming a loss of 15 pounds in 30 days.
Others claimed up to five-pound drops in weight within one month, taking one pill in the morning.
Consumers should be aware that extreme weight loss in a short amount of time also has the potential to destroy lean muscle. Slow and steady weight loss is preferred.
Many individuals who take this product are more interested in its benefits for pre-workout energy enhancement and athletic performance. It has been used to increase motivation to work out and improve power output and exercise intensity.
These individuals may not actually want the weight loss effects that are promised by the supplement. Athletes and bodybuilders who are expending large amounts of energy must also consume adequate nutritional intake. For some, finding the right balance can be difficult due to the appetite suppression effects of the product.
Reports of adverse effects can also be found in user reviews. Some users complain that it causes hot flashes, and some do experience an “energy crash”. For some, taking pills in the afternoon causes jitters and difficulty sleeping.
Some users describe splitting the product into one-half or one-fourth the recommended dosage to improve tolerance. Beginners should start with one-fourth pill in the morning to see how the body reacts to it before increasing the dosage.
The Hi Tech Lipodrene Hardcore label recommends taking one to two tablets in the morning and one tablet after lunch. They also warn not to exceed four tablets daily.
For some users, this dosage will be too high. Individual sensitivities to stimulant products can vary widely. Start at a low dose to gauge your initial tolerance, especially if you do not have experience with use of stimulant diet pills already.
Instructions also caution against consuming other products that contain caffeine, (including soda, tea, and coffee), as well as any product containing synephrine or other stimulants.
The label for this product does not provide the specific milligram strength of each of these ingredients. This can make it difficult to evaluate safety of the product.
Individuals may experience different results as well as potential side effects depending on their sensitivity to these ingredients.
Consult with a doctor before using to determine whether this product is appropriate for you. Drink lots of water if you use it and do not combine it with other medications before consulting with a qualified healthcare provider.
Is Lipodrene Hardcore Safe?
There is a risk of side effects when using Lipodrene diet pills or any other dietary supplements that promote stimulant-like effects. This product may not be safe for everyone to use.
Lipodrene Hardcore does not contain ephedra alkaloids such as ephedrine and pseudoephedrine, which are the components that have been banned in the United States by the Food and Drug Administration.
While controversy remains regarding some of the components found in Lipodrene Hardcore, the product has been used by thousands of individuals and is widely available online.
Consumers should always employ caution with the use of any weight-loss product based on its ingredients.
BMPEA is banned by the World Anti-Doping Agency because of its similarity to amphetamines, and the product has not been tested in clinical trials on humans.
Hi-Tech Pharmaceuticals did pay for a small clinical trial (composed of 10 men). The results showed that in this small group, heart rate did increase by 11 beats per minute and systolic pressure rose approximately 22 points. 
While many feel that the components found in dietary, weight loss, and energy-promoting products are not strong enough to cause serious side effects or adverse reactions, responses to many of the components found in such drugs is individualized.
Numerous studies have been conducted on the effects of caffeine, green tea, and some of the other ingredients found in weight loss and energy-boosting supplements. While these ingredients may be safe in isolation, their combination with other stimulants could increase the risk of dangerous effects.
One 2009 report in military medicine did associate ventricular fibrillation with use of p-Synephrine containing dietary supplements. 
Use of stimulant diet pills is contraindicated for anyone with cardiovascular problems or individuals taking monoamine oxidase inhibitors. Do not take Lipodrene Hardcore pills before first checking with a doctor about whether this product is appropriate for you.
Potential Side Effects
Use of Lipodrene Hardcore is reported to cause side effects in some users. Taking this product in high dosages or use in individuals with a high sensitivity to stimulants may be damngerous.
Products that contain ephedra, citrus aurantium, and caffeine, can cause shakiness or jitters in some users. This is in fact one of the ways that these products promote increased metabolism, by raising calorie expenditure associated with NEAT (Non-Exercise Activity Thermogenesis).
One of the primary concerns about some of the ingredients of Lipodrene Hardcore is the risk of increase blood pressure and heart rate. Some users have complained of severe heart palpitations, some lasting for a couple of hours, which can be worrisome.
Among the most common side effects linked to Lipodrene Hardcore include the aforementioned jitteriness, as well as:
- Nausea/upset stomach
- Increased anxiety
- Difficulty sleeping
Taking the product with food can ease nausea symptoms. Avoiding other stimulants, drinking lots of water and using it in low doses may minimize the risk of adverse effects.
Where Can You Buy Lipodrene Hardcore?
Lipodrene Hardcore can be found for sale at an average price of $35 per bottle for 90 tablets and has an MSRP of $70. It is not typically carried by brick-and-mortar stores such as The Vitamin Shoppe, GNC, CVS, Walgreens, Costco, Target, Rite-Aid or Wal-Mart.
This supplement is also not sold on the Amazon or eBay websites. It is currently listed as out-of-stock on the Hi-Tech Pharmaceuticals website. This product is sold by a small number of online specialty stores including:
- Ephedra Warehouse
- Ephedra Outlet
- Strong Supplement Shop
- My Supplement Store
- Black Diamond Supplements
Ephedra Legal Status
Many consumers are unsure of the legal status of ephedra-based dietary supplements in the United States and other countries. Is Lipodrene Hardcore legal if it contains ephedra, which has been banned by the FDA?
In the United States, ephedra extract is legal although the presence of ephedrine alkaloids in dietary supplements has been banned. Ephedrine is the active chemical found in the ephedra plant that is associated with many of its physiological effects.
This chemical compound is viewed as posing an unreasonably high risk of adverse effects according to the FDA. In 2004, they ruled that all fat burning containing ephedrine had to be removed from the market, including the original formula of Lipodrene with ephedra diet pills.
However, not all forms of ephedra were banned because not all forms of ephedra contain ephedrine alkaloids. The version found in the Lipodrene Hardcore ingredients list is called Thermo-Z. This is a proprietary blend of ephedra extract that is legal because it has its ephedrine alkaloids removed.
Therefore, Lipodrene Hardcore does not fall under the FDA’s ephedrine ban because it contains a legal form of ephedra extract.
Some controversy exists regarding the legal status of several other ingredients found in Lipodrene Hardcore. According to the FDA, this product contains other compounds that do not meet the definition of ingredients that are allowed in dietary supplements. This may explain why it is difficult to buy this product at the current time.
Hi-Tech Pharmaceuticals has long taken the position that the FDA is overreaching, especially when it comes to development of supplements that aid in weight loss or energy. When ephedra was banned by the FDA in 2004, Hi-Tech Pharmaceuticals disagreed with this ruling.
Today, Hi-Tech also disagrees with the FDA over their policy on new stimulant ingredients, such as DMAA in supplemental products. In 2013, the FDA ruled that it was not a legal dietary ingredient, but Hi-Tech argued that scientific proof and studies verifying dangers of such ingredients are lacking. 
At any rate, consumers should use Lipodrene Hardcore, or any weight-loss or energy producing supplement, with caution. Consult with a doctor first to learn about all of the potential side effects and risks of the product so you can make an informed decision about whether to use it.
- < a href="http://www.webmd.com/vitamins-and-supplements/news/20150407/bmpea-Acacia-rigudula-supplements#2" target="_blank">WebMD. Goodman Brenda, MA. Untested Stimulants Still in Dietary Supplements
- NBC News. Alexander, Brian. Hidden Speed: What is BMPEA and Why is it Dangerous?
- Stohs Sidney J., Preuss Harry G., Shara Mods. A Review of the Human Clinical Studies Involving Citrus aurantium (Bitter Orange) Extract and its Primary Protoalkaloid p-Synephrine. Int J Med Sci 2012; 9(7):527-538. doi:10.7150/ijms.4446
- NBC News. Alexander, Brian. Hidden Speed: What is BMPEA and Why is it Dangerous?
- Stephensen TA, Sarlay R Jr. Ventricular fibrillation associated with use of synephrine containing dietary supplement. Mil Med. 2009 Dec;174(12):1313-9
- Schultz Hank. Hi=Tech founder claims his devotion to DMAA is part of crusade against regulatory overreach.