How Long Does Ephedrine Last? [Half Life & Detection Time]

How long does ephedrine last in your body and what is the duration of the effects? Users generally feel the acute effects for 2-4 hours following taking a dosage and this plant extract has a half-life of 3-6 hours.

However, many things can affect how long a dose lasts and how long it takes to clear your system. Different people will metabolize this compound at different speeds and you may feel the effects for longer than other people do.

Ephedrine used to be one of the most popular fat burning and energy producing components found in over-the-counter weight-loss products – until 2004, when it was banned by the US Food and Drug Administration, soon followed by other countries around the world.

Ephedrine is an alkaloid that comes from the ephedra plant species. Not all subspecies of the ephedra herb family contain potent alkaloids, but some do.

While you can no longer purchase pure ephedrine from dietary supplements on store shelves today, it is still available, online and off – if you look in the right places. It comes in different forms, milligram strengths, potencies, and comes combined with different ingredients. Click here to buy ephedra supplements online legally without a prescription.

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How Long Does Ephedrine Last after I Use It?

How long does ephedrine last in my body after I use it? A number of factors may influence that answer.

A half-life is defined as the length of time that it takes the major activity or action of the drug to begin to wear off in the human body.

In general, the half-life of ephedrine is roughly three to five hours, but it also depends what form the product takes and where it came from. A person’s physical condition, size, body composition, and other factors may also influence the half-life of ephedrine.

In emergency medical situations, it’s designed as a treatment for hypotension or low blood pressure in a patient who is undergoing surgery, or other emergent scenarios.

This ingredient is also used as a vasodilator to open blood vessels and alleviate nasal congestion. All of these effects are attributed to its ability to stimulate the central nervous system by binding to beta-2 adrenergic receptors.

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Ephedrine Half-Life: How Does It Work?

When it comes to defining ephedrine half-life, it’s important to understand how it works and in what types of scenarios it would be used. During the half-life, a drug is working at optimal levels in the body.

Ephedrine acts as a stimulant on the central nervous system, and belongs to the class of alpha and beta-adrenergic agonists. An agonist is a trigger that influences some type of response in the body.

A number of adrenergic receptors are found in the human body, commonly found in arterial blood vessels.

Ephedrine works by influencing the release of norepinephrine, a neurotransmitter, in the brain. This causes arteries to constrict, increasing blood pressure and enhancing blood flow that returns to the heart for oxygenation.

The influence of ephedrine on beta receptors are focused on the heart muscle. As such, ephedrine can trigger the receptors in the heart to speed up heart rate and increase contractility, or the force with which the heart pumps blood out to the system.

Last but not least, ephedrine can have an influence on beta-2 receptors that are typically found in the lung airwaves. In this mechanism of action, ephedrine causes the airways to dilate or widen, increasing oxygen flow.

How Long Does It Take for Ephedrine to Start Working?

How long does it take for ephedrine to work, or start working in the body? In most cases, an individual will feel the effects within a very short time.

For some, and depending on sensitivity, effects can be felt within 20 minutes, while for some, it may be an hour. Again, body composition, age, physical status, and other factors will influence how long it takes for ephedrine to start working, as well as its half-life.

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How Long Does Ephedrine Stay in Your System?

How long does this compound remain detectable in your body, blood and urine? It depends on how much was taken, and in what form.

Ephedrine can be found as an oral capsule or tablet, a compounding powder, and in hospital scenarios, as an intravenous or injectable solution.

Athletes and bodybuilders don’t generally take the injectable solutions, but do find ephedrine in liquid form or in products containing ephedrine such as decongestants, asthma medicines, and cough and cold/flu medicines.

Each of these forms, and depending on how it’s taken and how it’s used, will have an influence on how long it stays in the body.

What To Know about an Ephedrine Drug Test

If you take ephedrine, you want to know how long ephedrine can stay in your system, especially if you’re preparing for a sporting event. Presence of ephedrine in the body will provide a positive test for amphetamine.

If any type of sporting event requires a blood test, be aware that ephedrine, when used by itself, has a half-life of three to six hours, but it won’t completely flush out of the bloodstream for at least two days. If taken with other ephedrine-like products, that half-life can be extended.

A urine test is the first and most popular type of test used to determine the presence of drugs in the system. In cases where an ephedrine drug test does show up as amphetamine in a drug test, individuals often claim that the response was a false positive for amphetamine.

It would behoove individuals undergoing drug tests or urine analysis for any job position, prior to a sporting event, or any other reason let the tester know if you have used ephedrine in the past few days.

Safety Considerations

Ephedrine, at least in the US and in many countries around the world, is defined as a prescription-only drug. It is not recommended for those who are pregnant due to unknown reactions and influences on a developing fetus or a nursing baby.

It is restricted under Controlled Substances Act in the United States and has an approved drug history by the Food and Drug Administration for medical purposes.

However, it is banned in dietary supplement ingredients. Athletes should be aware that ephedrine is a banned substance by the World Anti-Doping Agency and many other sporting agencies prohibit its use.

A large number of athletes have been suspended from professional and amateur competition for testing positive with ephedrine alkaloids.

A number of safety considerations are associated with use of this herbal extract in any form. Common symptoms associated with use include but are not limited to:

  • Racing heart
  • Heart palpitations
  • Dizziness
  • Blurred vision
  • Headaches

Because ephedrine behaves in a similar manner as amphetamine in the central nervous system, it is advised that it be used with caution and discretion.

In answer to the question, “How long does ephedrine last?” for either its effects or its half-life, it is strongly recommended that individuals learn as much as they can about the drug prior to use. Every individual may experience different potency and half-life of the compound.

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